Scientist - Cell Line Engineering
A leading biopharmaceutical company is seeking an experienced Scientist to join their Antibody Cell Line Sciences team. This group sits within the Antibody and Novel Therapeutics function and plays a key role in developing engineered mammalian cell lines that support the manufacture of innovative therapeutic antibodies and complex biologics. This is a hands-on laboratory role focused on host cell line development, cell line engineering, and optimisation of stable mammalian expression systems for antibody production. Key Responsibilities Establish and develop a toolbox of host cell lines suitable for manufacturing, applying strong laboratory-based scientific expertise Ensure host systems can express a diverse range of molecule types and meet GMP manufacturing requirements, supported by robust documentation Engineer and generate stable mammalian cell lines for antibody and novel antibody-format expression Apply a variety of host engineering and genome editing techniques to develop improved expression systems Analyse expression and engineering data to draw clear conclusions and inform next steps Work closely with molecular biology and engineering teams to drive technical progress Communicate progress effectively across multidisciplinary teams, highlighting risks, issues, and potential opportunities Maintain accurate documentation and records in line with scientific and regulatory standards Skills and Experience Minimum BSc in a relevant life sciences discipline Experience ..... full job details .....
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